Spinal stenosis – Diagnosis and treatment


To diagnose spinal stenosis, your doctor may ask you about signs and symptoms, discuss your medical history, and conduct a physical examination. He or she may order several imaging tests to help pinpoint the cause of your signs and symptoms.

Imaging tests

These tests may include:

  • X-rays. An X-ray of your back can reveal bony changes, such as bone spurs that may be narrowing the space within the spinal canal. Each X-ray involves a small exposure to radiation.
  • Magnetic resonance imaging (MRI). An MRI uses a powerful magnet and radio waves to produce cross-sectional images of your spine. The test can detect damage to your disks and ligaments, as well as the presence of tumors. Most important, it can show where the nerves in the spinal cord are being pressured.
  • CT or CT myelogram. If you can’t have an MRI, your doctor may recommend computerized tomography (CT), a
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ACLU asks judge to block Arkansas trans youth treatment ban | PA Power and Policy

LITTLE ROCK, Ark. (AP) — The American Civil Liberties Union on Tuesday asked a federal judge to prevent Arkansas from enforcing its ban on gender confirming treatments for transgender youth while a lawsuit challenging the prohibition proceeds.

The ACLU requested a preliminary injunction against the new law, which is set to take effect on July 28. It will prohibit doctors from providing gender confirming hormone treatment, puberty blockers or surgery to anyone under 18 years old, or from referring them to other providers for the treatment.

The ACLU filed a lawsuit challenging the ban last month on behalf of four transgender youth and their families, as well as two doctors who provide the treatments.

The ban is forcing some families of transgender youth to move out of state to continue their children’s treatments, if they can afford to do so, the filing contends.

“The threat of harm to plaintiffs is

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Bahrain approves emergency use for REGN-COV2 for COVID-19 treatment

Saudi Gazette report

MANAMA — Bahrain’s National Health Regulatory Authority (NHRA) has approved REGN-COV2 for emergency use, a new drug by Regeneron in collaboration with F. Hoffmann-La Roche, for the treatment of mild to moderate COVID-19 cases, the Bahrain News Agency reported on Wednesday.

REGN-COV2 contains a combination of Casirivimab and Imdevimab, which are drugs called “monoclonal antibodies,” that are designed to block viral attachment and entry into human cells to neutralize the virus.

REGN-COV2 also received emergency use approval from the US FDA to treat mild to moderate symptoms of COVID-19 in non-hospitalized adults and adolescents of 12 years of age and older, who weigh at least 88 pounds (40 kg), and for those who are at high risk for developing severe COVID-19 symptoms or of hospitalization.

REGN-COV2 also received a positive review from the European Medicines Agency after their analysis of the quality, safety, and efficacy aspects of

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Causes, Symptoms, Diagnosis, Treatment, and Complications

What Is Pleurisy?

Pleurisy is a type of chest pain. It affects a part of your body called the pleura.

The pleura is a thin layer of tissue that wraps your lungs. They fit snugly within your chest, which is lined with another thin layer of pleura.

These layers keep your bare lungs from rubbing against the wall of your chest cavity every time you breathe in. There’s a bit of fluid within the narrow space between the two layers of pleura to keep everything moving smoothly.

When you’re healthy, you never notice your pleura at work. But if your pleura has a problem, you’ll feel it.

When the pleurae are swollen and inflamed, they rub against each other in a very painful way each time your lungs expand. When you inhale deeply, cough, sneeze, or laugh, you’ll probably feel a sharp, stabbing pain in the area that’s affected.


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KSOM study reveals potential new treatment target in the fight against COVID-19

Images of cells showing close proximity (yellow) of GRP78 (green) with Spike protein of SARS-Cov-2 (red) (left panels) and ACE2 (red) (right panels). Image provided by lead author Anthony Carlos, PhD.

The swift development of vaccines has provided a vital tool to combat the spread of the deadly SARS-CoV-2 virus, but challenges to reaching herd immunity posed by the rise of new mutations and the inability of immunosuppressed people to develop an effective immune response following vaccination point to a need for additional solutions to maximize protection.

A new study by Keck School of Medicine (KSOM) researchers published in the Journal of Biological Chemistry reveals how therapies targeting a molecular chaperone called GRP78 might offer additional protection against COVID-19 and other coronaviruses that emerge in the future.

Chaperones like GRP78 are molecules that help regulate the correct folding of proteins, especially when a cell is under stress. But in some

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Oxford University explores anti-parasitic drug ivermectin as Covid-19 treatment | India News

NEW DELHI: The University of Oxford said on Wednesday it was testing anti-parasitic drug ivermectin as a possible treatment for Covid-19, as part of a British government-backed study that aims to aid recoveries in non-hospital settings.
Ivermectin resulted in a reduction of virus replication in laboratory studies, the university said, adding that a small pilot showed giving the drug early could reduce viral load and the duration of symptoms in some patients with mild Covid-19.
Dubbed PRINCIPLE, the British study in January showed that antibiotics azithromycin and doxycycline were generally ineffective against early-stage Covid-19.
While the World Health Organization, and European and US regulators have recommended against using ivermectin in Covid-19 patients, it is being used to treat the illness in some countries, including India.
“By including ivermectin in a large-scale trial like PRINCIPLE, we hope to generate robust evidence to determine how effective the treatment is against Covid-19, and
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Paradox devs clarify treatment of slavery and colonialism in ‘Victoria 3’

The developers behind Victoria 3 have revealed their working philosophy when including controversial historical subjects in their games.

  • READ MORE: ‘Empire Of Sin’: how Romero Games wrote a ballet of bullets

In a recent interview with PCGamesN, the Paradox developers behind Victoria 3 discussed the difficulties in representing time periods authentically. Set in the Victorian era, a major part of the narrative falls on slavery and colonialism, factors which the developers were keen to not leave out.

“We want to represent all of history,” game director Martin Anward explained. “We don’t want to represent just the nice parts of history, or parts that aren’t horrific. We are representing the entire world’s population.

“So for us to, for instance, write slavery out of the game, would mean that we are effectively writing [out] those people and their experiences, and all of what happened in history”.

The developers went on to

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Does Your Child Have a Peanut Allergy? Learn about a Treatment Option | Health & Wellness

(BPT) – Peanut allergy is the most common food allergy in children in the U.S. and affects approximately 1.3 million children between the ages of 4 through 17.1

If your child has a peanut allergy, you know firsthand the burden it can have on your family. It can be a life-long condition, and reactions to peanut can range from mild to potentially life-threatening.

Exposure to even a small amount of allergen can prompt an allergic reaction2; approximately one in five children with physician-diagnosed peanut allergy had at least one peanut-allergy related emergency department visit in a single year within the U.S.3

Practicing a strict peanut-free diet alone may not be enough. No matter how careful you are as a parent, a family, or a community, accidental exposure can still happen anytime, anywhere, and the constant vigilance can be exhausting. As a result, peanut allergy is associated

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Leukemia: Diagnosis, Tests, Treatment, Medication

A stem cell transplant has three stages: induction, conditioning, and transplantation. First, the individual’s white blood cell count is brought under control by chemotherapy. Then a single dose of chemotherapy may be given followed by a conditioning regimen of high dose chemotherapy. This will destroy the individual’s bone marrow and any residual leukemia cells that may be present. Then the donor cells will be infused.

Until the donor marrow cells start producing new blood, the individual is left with virtually no blood cells — white cells, red cells, or platelets. This makes death by infection or bleeding a strong possibility. Once the donor stem cells grow sufficiently into the marrow, usually in two to six weeks, long-term remission becomes a strong possibility. In addition to chemotherapy, the person will receive medication to prevent and treat graft versus host disease. With this disease, donor cells attack the person’s normal

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Ivermectin | COVID-19 Treatment Guidelines

Last Updated: February 11, 2021

Ivermectin is a Food and Drug Administration (FDA)-approved antiparasitic drug that is used to treat several neglected tropical diseases, including onchocerciasis, helminthiases, and scabies.1 It is also being evaluated for its potential to reduce the rate of malaria transmission by killing mosquitoes that feed on treated humans and livestock.2 For these indications, ivermectin has been widely used and is generally well tolerated.1,3 Ivermectin is not approved by the FDA for the treatment of any viral infection.

Proposed Mechanism of Action and Rationale for Use in Patients With COVID-19

Reports from in vitro studies suggest that ivermectin acts by inhibiting the host importin alpha/beta-1 nuclear transport proteins, which are part of a key intracellular transport process that viruses hijack to enhance infection by suppressing the host’s antiviral response.4,5 In addition, ivermectin docking may interfere with

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